Ruth Birner-Grünberger

Ruth Birner-Grünberger is an is a biochemist and Associate Professor at the Institute of Pathology of the Medical University of Graz.

Research interests:

Ruth Birner-Gruenberger is speaker of the Omics Center. She has extensive scientific experience in lipid metabolism, mass spectrometry, and proteomics. She has developed tools for activity-based profiling of lipases. This state-of-the art technique has proven extremely powerful in discovery, profiling and subcellular localization of active serine hydrolases.


  • Institute of Pathology / Center of Medical Research
    Medical University of Graz
    Stiftingtalstraße 24
    8010 Graz, Austria
  • Tel: +43 316 385-72962
    Fax: +43 316 385-73009
  • CV: link
  • Publications: link

Lab infrastructure:

  • High resolution mass spectrometers (Thermo LTQ-FT and Orbitrap velos pro, Bruker Ultraflexeme)
  • Software and servers for 2D gel image analysis (Delta2D), database search, posttranslational modifications (PTM) and quantitative data analysis, annotation and comparison (e. g. Mascot, Proteinscape, Proteome Discoverer, Sieve, Peaks, Cytoskape)
  • Mass spectrometry-based quantitative proteomic methods, including label-free approaches, such as spectral counting and retention time alignment and quantitation of areas of reconstructed ion chromatograms, as well as isotope labeling approaches such as dimethyllabeling, ICPL, i-TRAQ / TMT and metabolic labeling (stable isotope labeling with amino acids in cell culture, SILAC) and gel-based abundance-based protein profiling (DIGE)
  • Phosphoproteomics and acetylation proteomics