Ruth Birner-Grünberger is an is a biochemist and Associate Professor at the
Institute of Pathology
of the Medical University of Graz.
Ruth Birner-Gruenberger is speaker of the Omics Center.
She has extensive scientific experience in lipid metabolism, mass spectrometry, and proteomics. She has
developed tools for activity-based profiling of lipases. This state-of-the art technique has proven extremely
powerful in discovery, profiling and subcellular localization of active serine hydrolases.
Institute of Pathology / Center of Medical Research
Medical University of Graz
8010 Graz, Austria
Tel: +43 316 385-72962
Fax: +43 316 385-73009
- High resolution mass spectrometers (Thermo LTQ-FT and Orbitrap velos pro, Bruker Ultraflexeme)
- Software and servers for 2D gel image analysis (Delta2D), database search, posttranslational
modifications (PTM) and quantitative data analysis, annotation and comparison (e. g. Mascot, Proteinscape, Proteome Discoverer, Sieve, Peaks, Cytoskape)
- Mass spectrometry-based quantitative proteomic methods, including label-free approaches, such
as spectral counting and retention time alignment and quantitation of areas of reconstructed
ion chromatograms, as well as isotope labeling approaches such as dimethyllabeling, ICPL,
i-TRAQ / TMT and metabolic labeling (stable isotope labeling with
amino acids in cell culture, SILAC) and gel-based abundance-based protein profiling (DIGE)
- Phosphoproteomics and acetylation proteomics