Dagmar Kratky

Dagmar Kratky is a molecular biologist and Professor of Biochemistry at the Institute of Molecular Biology and Biochemistry of the Medical University of Graz.

Research interests:

Her research interest focuses on lipid metabolism and lipotoxicity in cells and tissues. Work in her lab includes generation of transgenic and knockout mouse models with varying lipid content in different cells and tissues to characterize whole-body and cell-autonomous lipid and energy metabolism, cell and tissue morphology and (dys)function. Energy metabolism with special emphasis on the role of lipolytic and lipid synthesizing enzymes and atherosclerosis susceptibility of mouse models are further areas of research. She has successfully explored the role of metabolic lipases (adipose triglyceride lipase, monoglyceride lipase) in macrophages and neutrophils. She is also deputy speaker of and principal investigator in the doctoral program “Metabolic and Cardiovascular Disease (DK-MCD)” supported by the Austrian Science Fund.


  • Institute of Molecular Biology and Biochemistry
    Medical University of Graz
    Harrachgasse 21/III
    8010 Graz, Austria
  • Tel: +43 316 380-7543
    Fax: +43 316 380-9615
  • CV: link
  • Publications: link

Lab infrastructure:

  • On-line metabolic cages (TSE PhenoMaster) including a temperature-controlled chamber for cooling experiments and at thermoneutrality
  • Flow cytometer (Millipore Guave8Cyte)
  • Cell culture facilities
  • Radionuclide laboratory
  • Biochemical, molecular biology and cell biology facilities
  • Proteomics platform: 2D-gel electrophoresis, MALDI-TOF, typhoon imager, gas chromatograph, fast protein liquid chromatography (FPLC)
  • XF24 Extracellular Flux Analyzer (Seahorse) for simultaneous measurements of oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) in cells and tissue slices.
  • Lipase-deficient mice on atherosclerotic backgrounds
  • Various global and tissue-specific knockout mouse model


Staining of valve sections from atherosclerotic mice with oil red O, MoMa-2, and Masson’s Trichrome to visualize lipids, macrophages, and collagen (blue), respectively.
Oil red O