Branislav Radović is is a molecular biologist and PD at the
Molecular Biology and Biochemistry
of the Medical University of Graz.
His main research interest is focused on lysosomal lipid degradation and the role of autophagy
(lipophagy) in energy homeostasis. He generates mouse models with cell- and tissue-specific
autophagy deficiency and investigates the consequences on lipid metabolism. He has recently
explored the functional role of lysosomal acid lipase in hepatic TG homeostasis and VLDL secretion.
In addition, he is very much interested in macrophage function of mutant mouse models.
Institute of Molecular Biology and Biochemistry
Medical University of Graz
8010 Graz, Austria
Tel: +43 316 380-4207
Fax: +43 316 380-9615
- On-line metabolic cages (TSE PhenoMaster) including a temperature-controlled chamber for cooling experiments and at thermoneutrality
- Flow cytometer (Millipore Guave8Cyte)
- Cell culture facilities
- Radionuclide laboratory
- Biochemical, molecular biology and cell biology facilities
- Proteomics platform: 2D-gel electrophoresis, MALDI-TOF, typhoon imager, gas chromatograph, fast protein liquid chromatography (FPLC)
- XF24 Extracellular Flux Analyzer (Seahorse) for simultaneous measurements of oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) in cells and tissue slices.
- Lipase-deficient mice on atherosclerotic backgrounds
- Various global and tissue-specific knockout mouse models